diff --git a/gnu/packages/python-crypto.scm b/gnu/packages/python-crypto.scm
index 50ec68b03ef..ac217f4ed7c 100644
--- a/gnu/packages/python-crypto.scm
+++ b/gnu/packages/python-crypto.scm
@@ -810,15 +810,10 @@ ECB and OFB).")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32
-         "1qsg06qrqnzixmrm65ibg503y2gffd675h1si4jgh92s315w1jrk"))))
-    (build-system python-build-system)
-    (arguments
-     '(#:phases (modify-phases %standard-phases
-                  (replace 'check
-                    (lambda* (#:key tests? #:allow-other-keys)
-                      (when tests?
-                        (invoke "python" "run.py" "tests")))))))
+        (base32 "1qsg06qrqnzixmrm65ibg503y2gffd675h1si4jgh92s315w1jrk"))))
+    (build-system pyproject-build-system)
+    (arguments (list #:test-backend #~'unittest))
+    (native-inputs (list python-setuptools))
     (home-page "https://github.com/wbond/asn1crypto")
     (synopsis "ASN.1 parser and serializer in Python")
     (description