diff --git a/gnu/packages/base.scm b/gnu/packages/base.scm
index 4909a375a1c..320081d818e 100644
--- a/gnu/packages/base.scm
+++ b/gnu/packages/base.scm
@@ -5,7 +5,7 @@
 ;;; Copyright © 2014, 2015, 2016, 2018 Mark H Weaver <mhw@netris.org>
 ;;; Copyright © 2014 Alex Kost <alezost@gmail.com>
 ;;; Copyright © 2014, 2015 Manolis Fragkiskos Ragkousis <manolis837@gmail.com>
-;;; Copyright © 2016, 2017, 2019-2023 Efraim Flashner <efraim@flashner.co.il>
+;;; Copyright © 2016, 2017, 2019-2023, 2025 Efraim Flashner <efraim@flashner.co.il>
 ;;; Copyright © 2016, 2020, 2023, 2024, 2025 Janneke Nieuwenhuizen <janneke@gnu.org>
 ;;; Copyright © 2016, 2018 Alex Vong <alexvong1995@gmail.com>
 ;;; Copyright © 2017 Rene Saavedra <rennes@openmailbox.org>
@@ -369,10 +369,15 @@ differences.")
      ;; XXX: On 32-bit Hurd platforms, 'time_t' is defined as a 32-bit
      ;; integer in 'hurd_types.defs', so this Gnulib test always fails.
      #:make-flags
-     #~#$(if (and (not (%current-target-system))
-                  (string=? (%current-system) "i586-gnu"))
-             #~'("XFAIL_TESTS=test-year2038")
-             #~'())
+     #~#$(cond ((and (not (%current-target-system))
+                     (string=? (%current-system) "i586-gnu"))
+                #~'("XFAIL_TESTS=test-year2038"))
+               ;; TODO: Figure out why these gnulib tests are failing.
+               ((and (not (%current-target-system))
+                     (target-ppc64le?))
+                #~'("XFAIL_TESTS=test-float-h large-subopt"))
+               (else
+                #~'()))
 
      #:configure-flags
      #~#$(if (%current-target-system)