diff --git a/gnu/packages/llvm.scm b/gnu/packages/llvm.scm
index cdfbaad7b7a..e082f23dc02 100644
--- a/gnu/packages/llvm.scm
+++ b/gnu/packages/llvm.scm
@@ -1292,6 +1292,89 @@ Library.")
 ;; toplevel variables cannot be called from one file to another.
 (define %rocm-llvm-version "7.1.0")
 
+(define %clang-rocm-supported-gpu-targets
+  ;; List of supported GPU targets for the current version of clang-rocm.
+  ;; This list can be obtained by running:
+  ;;
+  ;;   guix shell clang-rocm -- \
+  ;;     clang --target=amdgcn-amd-amdhsa -mcpu=help -nogpulib
+  ;;
+  ;; See also <https://llvm.org/docs/AMDGPUUsage.html#amdgpu-processor-table>.
+  ;; Update this list when upgrading clang-rocm.
+  '("bonaire"
+    "carrizo"
+    "fiji"
+    "generic"
+    "generic-hsa"
+    "gfx10-1-generic"
+    "gfx10-3-generic"
+    "gfx1010"
+    "gfx1011"
+    "gfx1012"
+    "gfx1013"
+    "gfx1030"
+    "gfx1031"
+    "gfx1032"
+    "gfx1033"
+    "gfx1034"
+    "gfx1035"
+    "gfx1036"
+    "gfx11-generic"
+    "gfx1100"
+    "gfx1101"
+    "gfx1102"
+    "gfx1103"
+    "gfx1150"
+    "gfx1151"
+    "gfx1152"
+    "gfx1153"
+    "gfx12-generic"
+    "gfx1200"
+    "gfx1201"
+    "gfx600"
+    "gfx601"
+    "gfx602"
+    "gfx700"
+    "gfx701"
+    "gfx702"
+    "gfx703"
+    "gfx704"
+    "gfx705"
+    "gfx801"
+    "gfx802"
+    "gfx803"
+    "gfx805"
+    "gfx810"
+    "gfx9-4-generic"
+    "gfx9-generic"
+    "gfx900"
+    "gfx902"
+    "gfx904"
+    "gfx906"
+    "gfx908"
+    "gfx909"
+    "gfx90a"
+    "gfx90c"
+    "gfx940"
+    "gfx941"
+    "gfx942"
+    "gfx950"
+    "hainan"
+    "hawaii"
+    "iceland"
+    "kabini"
+    "kaveri"
+    "mullins"
+    "oland"
+    "pitcairn"
+    "polaris10"
+    "polaris11"
+    "stoney"
+    "tahiti"
+    "tonga"
+    "tongapro"
+    "verde"))
+
 (define (make-llvm-rocm llvm-base)
   (package
     (inherit llvm-base)
@@ -1402,7 +1485,11 @@ This AMD fork includes AMD-specific additions."))))
                        #:test-target "check-clang" args)))
             (replace 'add-tools-extra
               (lambda _
-                (copy-recursively "../clang-tools-extra" "tools/extra")))))))))
+                (copy-recursively "../clang-tools-extra" "tools/extra")))))))
+
+    (properties
+     `((compiler-amd-gpu-targets . ,%clang-rocm-supported-gpu-targets)
+       ,@(package-properties clang-base)))))
 
 (define-public clang-rocm (make-clang-rocm clang-20))