diff --git a/CODEOWNERS b/CODEOWNERS
index ad2473c187b..3a502353c61 100644
--- a/CODEOWNERS
+++ b/CODEOWNERS
@@ -270,6 +270,7 @@ gnu/packages/librewolf\.scm                        @guix/mozilla
 gnu/packages/tor-browsers\.scm                     @guix/mozilla
 
 gnu/packages/ocaml\.scm                            @guix/ocaml
+gnu/packages/ocaml5\.scm                           @guix/ocaml
 gnu/packages/coq\.scm                              @guix/ocaml
 guix/build/ocaml-build-system\.scm                 @guix/ocaml
 guix/build/dune-build-system\.scm                  @guix/ocaml
diff --git a/etc/teams.scm b/etc/teams.scm
index b5dbc63e2f3..c87c9104f70 100755
--- a/etc/teams.scm
+++ b/etc/teams.scm
@@ -854,6 +854,7 @@ and Firefox."
 importer, and the ocaml-build-system."
         #:scope
         (list "gnu/packages/ocaml.scm"
+              "gnu/packages/ocaml5.scm"
               "gnu/packages/coq.scm"
               "guix/build/ocaml-build-system.scm"
               "guix/build/dune-build-system.scm"
diff --git a/gnu/local.mk b/gnu/local.mk
index f110841381f..b553f0019af 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -73,6 +73,7 @@
 # Copyright © 2024 James Smith <jsubuntuxp@disroot.org>
 # Copyright © 2025 Nigko Yerden <nigko.yerden@gmail.com>
 # Copyright © 2025 Cayetano Santos <csantosb@inventati.org>
+# Copyright © 2025 Jason Conroy <jconroy@tscripta.net>
 #
 # This file is part of GNU Guix.
 #
@@ -512,6 +513,7 @@ GNU_SYSTEM_MODULES =				\
   %D%/packages/nvi.scm				\
   %D%/packages/nx.scm				\
   %D%/packages/ocaml.scm			\
+  %D%/packages/ocaml5.scm			\
   %D%/packages/ocr.scm				\
   %D%/packages/openkinect.scm			\
   %D%/packages/onc-rpc.scm			\
diff --git a/gnu/packages/ocaml5.scm b/gnu/packages/ocaml5.scm
new file mode 100644
index 00000000000..d999952ea04
--- /dev/null
+++ b/gnu/packages/ocaml5.scm
@@ -0,0 +1,59 @@
+;;; GNU Guix --- Functional package management for GNU
+;;; Copyright © 2013 Cyril Roelandt <tipecaml@gmail.com>
+;;; Copyright © 2014, 2015 Mark H Weaver <mhw@netris.org>
+;;; Copyright © 2015 Andreas Enge <andreas@enge.fr>
+;;; Copyright © 2015 David Hashe <david.hashe@dhashe.com>
+;;; Copyright © 2016 Eric Bavier <bavier@member.fsf.org>
+;;; Copyright © 2016 Jan Nieuwenhuizen <janneke@gnu.org>
+;;; Copyright © 2016, 2018-2020, 2023, 2024 Efraim Flashner <efraim@flashner.co.il>
+;;; Copyright © 2016-2024 Julien Lepiller <julien@lepiller.eu>
+;;; Copyright © 2017 Ben Woodcroft <donttrustben@gmail.com>
+;;; Copyright © 2017, 2018, 2019, 2020 Tobias Geerinckx-Rice <me@tobias.gr>
+;;; Copyright © 2018 Peter Kreye <kreyepr@gmail.com>
+;;; Copyright © 2018, 2019 Gabriel Hondet <gabrielhondet@gmail.com>
+;;; Copyright © 2018 Kei Kebreau <kkebreau@posteo.net>
+;;; Copyright © 2019 Ricardo Wurmus <rekado@elephly.net>
+;;; Copyright © 2020 Brett Gilio <brettg@gnu.org>
+;;; Copyright © 2020 Marius Bakke <marius@gnu.org>
+;;; Copyright © 2020, 2021, 2025 Simon Tournier <zimon.toutoune@gmail.com>
+;;; Copyright © 2020 divoplade <d@divoplade.fr>
+;;; Copyright © 2020, 2021, 2022 pukkamustard <pukkamustard@posteo.net>
+;;; Copyright © 2021 aecepoglu <aecepoglu@fastmail.fm>
+;;; Copyright © 2021 Sharlatan Hellseher <sharlatanus@gmail.com>
+;;; Copyright © 2021 Xinglu Chen <public@yoctocell.xyz>
+;;; Copyright © 2021 Ivan Gankevich <i.gankevich@spbu.ru>
+;;; Copyright © 2021 Maxime Devos <maximedevos@telenet.be>
+;;; Copyright © 2021 Sarah Morgensen <iskarian@mgsn.dev>
+;;; Copyright © 2022 Maxim Cournoyer <maxim@guixotic.coop>
+;;; Copyright © 2022 John Kehayias <john.kehayias@protonmail.com>
+;;; Copyright © 2022 Garek Dyszel <garekdyszel@disroot.org>
+;;; Copyright © 2023 Csepp <raingloom@riseup.net>
+;;; Copyright © 2023, 2024 Foundation Devices, Inc. <hello@foundation.xyz>
+;;; Copyright © 2023 Arnaud DABY-SEESARAM <ds-ac@nanein.fr>
+;;; Copyright © 2024 Sören Tempel <soeren@soeren-tempel.net>
+;;; Copyright © 2025 Jussi Timperi <jussi.timperi@iki.fi>
+;;; Copyright © 2025 Jason Conroy <jconroy@tscripta.net>
+;;;
+;;; This file is part of GNU Guix.
+;;;
+;;; GNU Guix is free software; you can redistribute it and/or modify it
+;;; under the terms of the GNU General Public License as published by
+;;; the Free Software Foundation; either version 3 of the License, or (at
+;;; your option) any later version.
+;;;
+;;; GNU Guix is distributed in the hope that it will be useful, but
+;;; WITHOUT ANY WARRANTY; without even the implied warranty of
+;;; MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+;;; GNU General Public License for more details.
+;;;
+;;; You should have received a copy of the GNU General Public License
+;;; along with GNU Guix.  If not, see <http://www.gnu.org/licenses/>.
+
+(define-module (gnu packages ocaml5)
+  #:use-module ((guix build-system ocaml)
+                #:select ((ocaml5-build-system . ocaml-build-system))))
+;;;
+;;; Avoid adding new packages to the end of this file. To reduce the chances
+;;; of a merge conflict, place them above by existing packages with similar
+;;; functionality or similar names.
+;;;