diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index e1620d73b86..d22691422cd 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -6721,6 +6721,12 @@ CWL descriptions.")
            (with-imported-modules `((guix build guile-build-system)
                                     ,@%default-gnu-imported-modules)
              #~(modify-phases %standard-phases
+                 (replace 'patch-source-shebangs
+                   (lambda* (#:key inputs #:allow-other-keys)
+                     (substitute* "bin/ravanan"
+                       (("^exec guile")
+                        (string-append "exec "
+                                       (search-input-file inputs "/bin/guile"))))))
                  (delete 'configure)
                  (add-after 'install 'wrap
                    (lambda* (#:key inputs outputs #:allow-other-keys)