diff --git a/gnu/packages/medical.scm b/gnu/packages/medical.scm
index 68a9260cf6e..8e344b6dd61 100644
--- a/gnu/packages/medical.scm
+++ b/gnu/packages/medical.scm
@@ -2,6 +2,7 @@
 ;;; Copyright © 2017 Ricardo Wurmus <rekado@elephly.net>
 ;;; Copyright © 2017 Quiliro <quiliro@fsfla.org>
 ;;; Copyright © 2022 Petr Hodina <phodina@protonmail.com>
+;;; Copyright © 2025 Jake Forster <jakecameron.forster@gmail.com>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -19,23 +20,40 @@
 ;;; along with GNU Guix.  If not, see <http://www.gnu.org/licenses/>.
 
 (define-module (gnu packages medical)
+  #:use-module (guix build-system cmake)
   #:use-module (guix build-system pyproject)
   #:use-module (guix build-system python)
   #:use-module (guix build-system qt)
   #:use-module (guix download)
   #:use-module (guix gexp)
-  #:use-module (guix licenses)
+  #:use-module (guix hg-download)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (guix packages)
+  #:use-module (gnu packages base)
   #:use-module (gnu packages bash) ; wrap-program
+  #:use-module (gnu packages boost)
+  #:use-module (gnu packages check)
+  #:use-module (gnu packages compression)
+  #:use-module (gnu packages curl)
   #:use-module (gnu packages databases)
+  #:use-module (gnu packages documentation)
+  #:use-module (gnu packages image)
+  #:use-module (gnu packages image-processing)
   #:use-module (gnu packages kde-frameworks) ; kirigami
+  #:use-module (gnu packages linux)
+  #:use-module (gnu packages lua)
+  #:use-module (gnu packages protobuf)
   #:use-module (gnu packages python)
   #:use-module (gnu packages python-build)
   #:use-module (gnu packages python-crypto)
   #:use-module (gnu packages python-web)
   #:use-module (gnu packages python-xyz)
-  #:use-module (gnu packages qt))
+  #:use-module (gnu packages qt)
+  #:use-module (gnu packages serialization)
+  #:use-module (gnu packages sqlite)
+  #:use-module (gnu packages tls)
+  #:use-module (gnu packages web)
+  #:use-module (gnu packages xml))
 
 (define-public mygnuhealth
   (package
@@ -125,3 +143,73 @@ functionality includes appointments, patient records, treatment planning,
 billing etc.  It is a full featured, reliable and thoroughly tested
 application and has been translated into many languages.")
     (license license:gpl3+)))
+
+(define-public orthanc
+  (package
+    (name "orthanc")
+    (version "1.12.7")
+    (source
+     (origin
+       (method hg-fetch)
+       (uri (hg-reference (url "https://orthanc.uclouvain.be/hg/orthanc")
+                          (changeset "a30cc2fa7250")))
+       (file-name (hg-file-name name version))
+       (sha256
+        (base32 "1n8v0dh17g9ihny8cpq63qd6ai5l95i5h3sz9vwzfnd7q3qh0rb9"))))
+    (build-system cmake-build-system)
+    (arguments
+     (list
+      #:configure-flags
+      #~(list (string-append "-DDCMTK_DICTIONARY_DIR="
+                             #$(this-package-input "dcmtk") "/share/dcmtk-"
+                             #$(package-version (this-package-input "dcmtk")))
+              ;; Building Connectivity Checks plugin requires the network.
+              "-DBUILD_CONNECTIVITY_CHECKS=OFF"
+              ;; Disable 4 tests that require the network.
+              "-DUNIT_TESTS_WITH_HTTP_CONNEXIONS=OFF")
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'chdir
+            (lambda _
+              ;; The OrthancServer/ subdirectory contains the root
+              ;; CMakeLists.txt file.
+              (chdir "OrthancServer")))
+          (add-after 'unpack 'remove-localtime-requirement
+            (lambda _
+              ;; /etc/localtime is not present in the build container;
+              ;; don't let that stop the build.
+              (substitute* "OrthancFramework/Sources/Toolbox.cpp"
+                (("if \\(!SystemToolbox::IsExistingFile\\(LOCALTIME\\)\\)")
+                 "if (false)"))))
+          ;; There is no test target; simply run the binary.
+          (replace 'check
+            (lambda* (#:key tests? #:allow-other-keys)
+              (when tests?
+                (invoke "./UnitTests")))))))
+    (native-inputs (list doxygen
+                         glibc-utf8-locales ;for one test
+                         googletest
+                         python))
+    (inputs (list boost
+                  civetweb
+                  curl
+                  dcmtk
+                  jsoncpp
+                  libjpeg-turbo
+                  libpng
+                  lua
+                  openssl
+                  protobuf
+                  pugixml
+                  `(,util-linux "lib")  ;for uuid.h
+                  sqlite
+                  unzip))
+    (home-page "https://orthanc-server.com")
+    (synopsis
+     "Standalone @acronym{DICOM, Digital Imaging and Communications in
+Medicine} server")
+    (description
+     "Orthanc is a standalone @acronym{DICOM, Digital Imaging and
+Communications in Medicine} server with a RESTful API and plugin
+mechanism for extending its functionality.")
+    (license license:gpl3+)))